RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
mir-200a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
rattus norvegicus
Detection Methods
immunohistochemistry; dual-lucimmunofluorescenceerase reporter assay etc.
Target
SIRT1
Pathway
SIRT1; NOTCH SIGNALING PATHWAY
PubMed ID
Title
MiR-200a controls hepatic stellate cell activation and fibrosis via SIRT1/Notch1 signal pathway
Year
2017
Function
Mir-200a inhibits hepatic stellate cell activation and fibrosis by inhibiting the sirt1 ; Notch1 signaling pathway.